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CUPID Platform
Screening
System

Cell-based Un-identified Protein Interaction Discovery

is an innovative and useful PPI inhibitor screening platform.

Better
Human
Life

bHLBIO develops the innovative drug for
the healthy human life, using our novel CUPID
platform which can monitor in real time
the Protein-Protein Interaction (PPI) in living cell.

CUPID Platform

Cell-based Un-identified Protein Interaction Discovery


PPI inhibitor screening platform

CUPID analysis Inhibition of p53-mdm2 PPI by Nutlin-3
[Nutlin-3: p53-MDM2 PPI inhibitos]
PPI Interaction
Nutlin-3 (-)
PPI Interaction inhibited
Nutlin-3 (+)

Business Area

bHLBIO uses a "Cell-based Un-/Identified Protein Interaction Discovery (CUPID) platform" to

develop innovative compounds or peptide drugs (mainly anti-cancer drugs).


  • KRAS-BRAF Showed better anti-proliferation

    activity
    and lower toxicity than

    Boehringer
    Ingelheim’s BI-3406

  • REV3-REV7 Minimum size binding

    fragment to
    REV7(20 aa)

    Peptide drug candidate

  • MYC-MAX Validated newly defined Myc-Max

    PPI
    interface and Developed

    Myc-Max PPI
    screening system (CUPID)